Case Western Reserve University — Research Assistant 1


Working under moderate supervision, the Research Assistant 1 will perform research on the molecular genetics of meiosis. The position will be responsible for performing routine molecular biology techniques, carrying out Drosophila genetic crosses and general lab maintenance.


  1. Maintain Drosophila stocks, perform routine Drosophila husbandry, generate new Drosophila mutants using CRISPR/Cas9, record and analyze Drosophila visible phenotypes to measure crossover frequencies and carry out Drosophila genetic crosses in support of the lab’s research program. (50%)
  2. Perform molecular biology techniques in support of the lab’s research program, including but not limited to PCR, Sanger sequencing, cloning and bacterial transformation. (30%).
  3. Perform confocal imaging of fluorescently labeled Drosophila ovaries. Collect and record results of experiments and closely related series of experiments. (7%)
  4. Maintain accurate records of experiments in lab notebooks and databases. (6%)
  5. Maintain test equipment utilized in experiments. Perform general lab maintenance. Responsible for general lab organization, cleanliness, ordering laboratory supplies and Environmental Health and Safety compliance. (7%) 

Perform other duties as assigned. (<1%)

Department: Daily contact with the principal investigator to coordinate research experiments, daily contact with students and other members of the lab in support of the lab’s research program. Occasional contact with other labs in the department to coordinate sharing of resources. 

University: Occasional contact with other departments to coordinate sharing of resources.

External: Limited or no contact with vendors to exchange information.

Students: Daily contact with student employees in order to support student research including ordering reagents and helping with experiments.

This position has no direct supervision of staff employees.

Education/Experience: Bachelor’s degree and 0 to 1 year of experience or Associate’s degree in an approved biotechnology program and 0 to 2 years of experience required. Undergraduate research experience preferred. 


  1. Knowledge of commonly used concepts, practices and procedures used for molecular biology and genetics, including PCR, Sanger sequencing, cloning methods, bacterial transformation, gel electrophoresis, sterile technique and reagent preparation.
  2. Ability to rely on verbal instructions and protocols to perform experiments after initial training. 
  3. Demonstrated attention to detail, organization skills and project management.
  4. Must be committed to fostering a positive lab environment, which includes supporting peers and mentoring students.
  5. Ability to meet consistent attendance.
  6. Ability to interact with colleagues, supervisors and customers face to face.

The Crown Lab is a general molecular biology and Drosophila genetics lab. There will be minimal exposure to hazardous chemicals over the course of routine experiments, but appropriate personal protective equipment will be provided. The employee will experience repetitive motion during Drosophila husbandry and routine pipetting. 

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity.  Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.

Case Western Reserve University provides reasonable accommodations to applicants with disabilities.  Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation.  Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

CWRU offers a flexible benefits package including tuition waiver for employees and dependents; Respond in confidence, including salary history : CASE WESTERN RESERVE UNIVERSITY, Human Resources Job Code #8884 apply to: